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Handbook of toxicologic pathology

Record Type:	Electronic resources : Monograph/item
Title/Author:	Handbook of toxicologic pathology/ edited by Wanda M. Haschek, Colin G. Rousseaux, Matthew A. Wallig.
other author:	Haschek, Wanda M.
Published:	San Diego :Academic Press, : c2002.,
Description:	1 online resource (2 v.) :ill. :
Subject:	Toxicology. -
Online resource:	http://www.sciencedirect.com/science/book/9780123302151
ISBN:	9780123302151

Handbook of toxicologic pathology
Handbook of toxicologic pathology[electronic resource] /edited by Wanda M. Haschek, Colin G. Rousseaux, Matthew A. Wallig. - 2nd ed. - San Diego :Academic Press,c2002. - 1 online resource (2 v.) :ill.

Includes bibliographical references and index.

Volume 1: General Toxicologic Pathology -- Preface. -- Contributors. -- Part A: Basics of Toxicologic Pathology -- Toxicologic Pathology: An Introduction. -- Biochemical Basis of Toxicity. -- Morphologic Manifestation of Toxic Cell Injury. -- Organelle Biochemistry and Regulation of Cell Death. -- Carcinogenesis. -- Applied Clinical Pathology in Preclinical Toxicology Testing. -- Nomenclature. -- Part B: The Practice of Toxicologic Pathology -- Basic Techniques. -- Managing Pitfalls in Toxicologic Pathology. -- Special Techniques in Toxicologic Pathology. -- Application of New Technologies to Toxicologic Pathology. -- Issues in Laboratory Animal Science for the Toxicologic Pathologist. -- New Animal Models in Toxicology. -- Pathology Issues in the Design of Toxicology Studies. -- Use and Misuse of Statistics in the Design and Interpretation of Studies. -- Preparation of the Report for a Toxicology/Pathology Study. -- Part C: Selected Topics in Toxicologic Pathology -- Risk Assessment: The Changing Paradigm. -- Principles of Risk Communication: Building Trust and Credibility with the Public. -- Biomedical Devices and Biomaterials. -- Biotechnology and Its Products. -- Endocrine Disruptors. -- Radiation and Heat. -- Nutritional Toxicologic Pathology. -- Phycotoxins. -- Mycotoxins. -- Heavy Metals. -- Volume 2: Organ Specific Toxicologic Pathology -- Organ-Specific Toxicologic Pathology: An Introduction. -- Respiratory System. -- Skin and Oral Mucosa. -- Gastrointestinal Tract. -- Liver. -- Pancreas. -- Kidney. -- Lower Urinary Tract. -- Cardiovascular and Skeletal Muscle Systems. -- Bones and Joints. -- Nervous System. -- The Eye. -- Immune System. -- Hematopoietic System. -- Endocrine System. -- Male Reproduction. -- Female Reproduction. -- Embryo and Fetus. -- Index.

A comprehensive understanding of toxicologic pathology is essential for those in industry, academia, and government who make decisions concerning the safety and efficacy of drugs and chemicals. Toxicologic Pathology relies heavily on the fields of both toxicology and pathology, which are well covered individually in various texts and references; however, there are few texts that address the field of toxicologic pathology. The Handbook of Toxicology Pathology fills this void and is thus essential for all health professionals within or interacting with the field of toxicologic pathology. This two-volume set provides the reader with a single reference for toxicologic pathology. In volume I, the book covers toxicologic pathology in its basic aspects, including its definition, the basic biochemical and morphologic mechanisms underlying the discipline, the basic practice of toxicologic pathology (including special techniques) and issues essential to the understanding of toxicologic pathology such as risk assessment, experimental design, and statistical analysis. Next, the book moves to specific issues affecting the "practice" toxicologic pathology, including issues such as knowledge management, regulatory affairs and writing pathology reports. Finally, Volume I closes with several chapters that deal with specific classes of environmental toxicants such as endocrine disruptors and heavy metals. Volume II addresses the toxicologic pathology in a thoroughly standardized systems manner, addressing the basic structure and function of a particular organ system, its response to toxic injury, mechanisms of injury and methods of evaluation of such injury. Key Features * Easy to find, up-to-date reference information * Graphic and photographic plates * Current hot topics and anticipated changes in toxicologic pathology * Standardized chapter format * Topics that are addressed in both a broad and deep manner, resulting in a stand alone text * Added coverage of important environmental toxicants * Chapters authored by internationally recognized experts and peer-reviewed.

ISBN: 9780123302151

Source: 88684:88684Elsevier Science & Technologyhttp://www.sciencedirect.comSubjects--Topical Terms:

201840
Toxicology.
Index Terms--Genre/Form:

96803
Electronic books.

LC Class. No.: RA1211 / .H3196 2002eb

Dewey Class. No.: 615.9

Universal Decimal Class. No.: 615.9 (02) P2.2

National Agricultural Library Call No.: RA1199.4.A54 / H36 2001

National Library of Medicine Call No.: 2002 N-790

Handbook of toxicologic pathology
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245 0 0 $a Handbook of toxicologic pathology $h [electronic resource] / $c edited by Wanda M. Haschek, Colin G. Rousseaux, Matthew A. Wallig.
250 $a 2nd ed.
260 $a San Diego : $c c2002. $b Academic Press,
300 $a 1 online resource (2 v.) : $b ill.
504 $a Includes bibliographical references and index.
505 0 $a Volume 1: General Toxicologic Pathology -- Preface. -- Contributors. -- Part A: Basics of Toxicologic Pathology -- Toxicologic Pathology: An Introduction. -- Biochemical Basis of Toxicity. -- Morphologic Manifestation of Toxic Cell Injury. -- Organelle Biochemistry and Regulation of Cell Death. -- Carcinogenesis. -- Applied Clinical Pathology in Preclinical Toxicology Testing. -- Nomenclature. -- Part B: The Practice of Toxicologic Pathology -- Basic Techniques. -- Managing Pitfalls in Toxicologic Pathology. -- Special Techniques in Toxicologic Pathology. -- Application of New Technologies to Toxicologic Pathology. -- Issues in Laboratory Animal Science for the Toxicologic Pathologist. -- New Animal Models in Toxicology. -- Pathology Issues in the Design of Toxicology Studies. -- Use and Misuse of Statistics in the Design and Interpretation of Studies. -- Preparation of the Report for a Toxicology/Pathology Study. -- Part C: Selected Topics in Toxicologic Pathology -- Risk Assessment: The Changing Paradigm. -- Principles of Risk Communication: Building Trust and Credibility with the Public. -- Biomedical Devices and Biomaterials. -- Biotechnology and Its Products. -- Endocrine Disruptors. -- Radiation and Heat. -- Nutritional Toxicologic Pathology. -- Phycotoxins. -- Mycotoxins. -- Heavy Metals. -- Volume 2: Organ Specific Toxicologic Pathology -- Organ-Specific Toxicologic Pathology: An Introduction. -- Respiratory System. -- Skin and Oral Mucosa. -- Gastrointestinal Tract. -- Liver. -- Pancreas. -- Kidney. -- Lower Urinary Tract. -- Cardiovascular and Skeletal Muscle Systems. -- Bones and Joints. -- Nervous System. -- The Eye. -- Immune System. -- Hematopoietic System. -- Endocrine System. -- Male Reproduction. -- Female Reproduction. -- Embryo and Fetus. -- Index.
520 $a A comprehensive understanding of toxicologic pathology is essential for those in industry, academia, and government who make decisions concerning the safety and efficacy of drugs and chemicals. Toxicologic Pathology relies heavily on the fields of both toxicology and pathology, which are well covered individually in various texts and references; however, there are few texts that address the field of toxicologic pathology. The Handbook of Toxicology Pathology fills this void and is thus essential for all health professionals within or interacting with the field of toxicologic pathology. This two-volume set provides the reader with a single reference for toxicologic pathology. In volume I, the book covers toxicologic pathology in its basic aspects, including its definition, the basic biochemical and morphologic mechanisms underlying the discipline, the basic practice of toxicologic pathology (including special techniques) and issues essential to the understanding of toxicologic pathology such as risk assessment, experimental design, and statistical analysis. Next, the book moves to specific issues affecting the "practice" toxicologic pathology, including issues such as knowledge management, regulatory affairs and writing pathology reports. Finally, Volume I closes with several chapters that deal with specific classes of environmental toxicants such as endocrine disruptors and heavy metals. Volume II addresses the toxicologic pathology in a thoroughly standardized systems manner, addressing the basic structure and function of a particular organ system, its response to toxic injury, mechanisms of injury and methods of evaluation of such injury. Key Features * Easy to find, up-to-date reference information * Graphic and photographic plates * Current hot topics and anticipated changes in toxicologic pathology * Standardized chapter format * Topics that are addressed in both a broad and deep manner, resulting in a stand alone text * Added coverage of important environmental toxicants * Chapters authored by internationally recognized experts and peer-reviewed.
588 $a Description based on print version record.
650 0 $a Toxicology. $3 201840
650 0 $a Physiology, Pathological. $3 84139
650 0 $a Veterinary toxicology. $3 228653
650 1 2 $a Poisoning $x pathology. $3 255387
650 6 $a Toxicologie $x Modeles animaux $v Guides, manuels, etc. $3 255388
650 6 $a Toxicologie experimentale $v Guides, manuels, etc. $3 255389
650 6 $a Pathologie experimentale $v Guides, manuels, etc. $3 255390
655 4 $a Electronic books. $2 local. $3 96803
700 1 $a Haschek, Wanda M. $3 255384
700 1 $a Rousseaux, Colin George, $d 1954- $3 255385
700 1 $a Wallig, Matthew A. $3 255386
776 0 8 $i Print version: $t Handbook of toxicologic pathology. $b 2nd ed. $d San Diego : Academic Press, c2002 $z 0123302153 $z 9780123302151 $w (DLC) 2001088191 $w (OCoLC)47901438
856 4 0 $3 ScienceDirect $u http://www.sciencedirect.com/science/book/9780123302151