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Single molecule biology

Record Type:	Electronic resources : Monograph/item
Title/Author:	Single molecule biology/ edited by Alexander E. Knight.
other author:	Knight, Alexander E.
Published:	London :Academic, : 2008.,
Description:	p.cm.;
Subject:	Molecular biology. -
Online resource:	An electronic book accessible through the World Wide Web; click for information
ISBN:	9780123742278

Single molecule biology
Single molecule biology[electronic resource] /edited by Alexander E. Knight. - London :Academic,2008. - p.cm.

Introduction and Historical Perspective; Motor Proteins: Linear Motors; Actin and Tubulin-Based Motors; DNA Motors; Rotary Motors; Single Molecule Enzymology; Ribozymes; Ribosomes; Large Complexes; Membrane Proteins; Channels and Pores; Cytoskeleton; DNA Mechanics and Structure; Single Molecules in Cells; Hair Cells; Structure of Single Protein Molecules; Single Molecule Mechanical Properties; Single Molecule Applications: Diagnostics; Single Molecule Applications: Arrays; Single Molecule Applications: Drug Discovery.

Single molecule techniques, including single molecule fluorescence, optical tweezers, and scanning probe microscopy, allow for the manipulation and measurement of single biological molecules within a live cell or in culture. These approaches, amongst the most exciting tools available in biology today, offer powerful new ways to elucidate biological function, both in terms of revealing mechanisms of action on a molecular level as well as tracking the behaviour of molecules in living cells. This book provides the first complete and authoritative treatment of this rapidly emerging field, explicitly from a biological perspective. The contents are organized by biological system or molecule. Each chapter discusses insights that have been revealed about their mechanism, structure or function by single molecule techniques. Among the topics covered are enzymes, motor proteins, membrane channels, DNA, ribozymes, cytoskeletal proteins, and other key molecules of current interest. An introduction by the editor provides a concise review of key principles and an historical overview. The last section discusses applications in molecular diagnostics and drug discovery. * Organized by biological system or molecule. * Each chapter discusses insights into mechanism of action, structure, and function * Covers enzymes, motor proteins, membrane channels, DNA, ribozymes, etc. * Includes an introduction to key principles and an historical overview. * Discusses applications in molecular diagnostics and drug discovery. * Provides an expert?s perspective on future developments.

Electronic reproduction.
Amsterdam :
Elsevier Science & Technology,
2008.

Mode of access: World Wide Web.

ISBN: 9780123742278

Source: 138469:138606Elsevier Science & Technologyhttp://www.sciencedirect.comSubjects--Topical Terms:

83096
Molecular biology.
Index Terms--Genre/Form:

96803
Electronic books.

Dewey Class. No.: 572.8

Single molecule biology
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020 $a 9780123742278
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037 $a 138469:138606 $b Elsevier Science & Technology $n http://www.sciencedirect.com
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245 0 0 $a Single molecule biology $h [electronic resource] / $c edited by Alexander E. Knight.
260 $a London : $c 2008. $b Academic,
300 $a p. $c cm.
505 0 $a Introduction and Historical Perspective; Motor Proteins: Linear Motors; Actin and Tubulin-Based Motors; DNA Motors; Rotary Motors; Single Molecule Enzymology; Ribozymes; Ribosomes; Large Complexes; Membrane Proteins; Channels and Pores; Cytoskeleton; DNA Mechanics and Structure; Single Molecules in Cells; Hair Cells; Structure of Single Protein Molecules; Single Molecule Mechanical Properties; Single Molecule Applications: Diagnostics; Single Molecule Applications: Arrays; Single Molecule Applications: Drug Discovery.
520 $a Single molecule techniques, including single molecule fluorescence, optical tweezers, and scanning probe microscopy, allow for the manipulation and measurement of single biological molecules within a live cell or in culture. These approaches, amongst the most exciting tools available in biology today, offer powerful new ways to elucidate biological function, both in terms of revealing mechanisms of action on a molecular level as well as tracking the behaviour of molecules in living cells. This book provides the first complete and authoritative treatment of this rapidly emerging field, explicitly from a biological perspective. The contents are organized by biological system or molecule. Each chapter discusses insights that have been revealed about their mechanism, structure or function by single molecule techniques. Among the topics covered are enzymes, motor proteins, membrane channels, DNA, ribozymes, cytoskeletal proteins, and other key molecules of current interest. An introduction by the editor provides a concise review of key principles and an historical overview. The last section discusses applications in molecular diagnostics and drug discovery. * Organized by biological system or molecule. * Each chapter discusses insights into mechanism of action, structure, and function * Covers enzymes, motor proteins, membrane channels, DNA, ribozymes, etc. * Includes an introduction to key principles and an historical overview. * Discusses applications in molecular diagnostics and drug discovery. * Provides an expert?s perspective on future developments.
533 $a Electronic reproduction. $b Amsterdam : $c Elsevier Science & Technology, $d 2008. $n Mode of access: World Wide Web. $n System requirements: Web browser. $n Title from title screen (viewed on Sep. 8, 2008). $n Access may be restricted to users at subscribing institutions.
650 0 $a Molecular biology. $3 83096
655 7 $a Electronic books. $2 local. $3 96803
700 1 $a Knight, Alexander E. $3 292217
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776 1 $c Original $z 9780123742278 $z 0123742277 $w (OCoLC)244648152
856 4 0 $3 ScienceDirect $u http://www.sciencedirect.com/science/book/9780123742278 $z An electronic book accessible through the World Wide Web; click for information
938 $a Baker and Taylor $b BTCP $n BK0007846717
994 $a C0 $b TEF