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Essentials of genomic and personalized medicine

紀錄類型:	書目-電子資源 : 單行本
正題名/作者:	Essentials of genomic and personalized medicine/ edited by Geoffrey S. Ginsburg and Huntington F. Willard.
其他作者:
出版者:	Amsterdam ;Academic, : 2010.,
面頁冊數:	xx, 830 p. :ill. (some col.) ; : 29 cm.;
標題:
ISBN:	9780123749345

Essentials of genomic and personalized medicine
Essentials of genomic and personalized medicine[electronic resource] /edited by Geoffrey S. Ginsburg and Huntington F. Willard. - 1st ed. - Amsterdam ;Academic,2010. - xx, 830 p. :ill. (some col.) ;29 cm.

1�Introduction -- �Section 1 - Basics -- 2�Organization, Variation and Expression of the Human Genome -- 3�DNA Sequencing for the Detection?of Human Genome Variation -- 4�Genome-Wide Association Studies and Genotyping Technologies -- 5�Copy Number Variation and Human Health -- 6�DNA Methylation Analysis: Providing New Insight into Human Disease -- 7�DNA Microarrays in Biological Diversity and Patient Care -- 8�Proteomics: The Deciphering of the Functional Genome -- 9�Comprehensive Metabolic Analysis for Understanding Disease -- �Section 2 - Informatics -- 10�Bioinformatic and Computational Analysis for Genomic Medicine -- 11�Systems Biology and Systems Medicine -- 12�Electronic Medical Records in Genomic Medicine Practice and Research -- 13�Health Information Retrieval for Consumers -- �Section 3 - Translational -- 14�Genomics to Health:?Challenges and Opportunities -- 15�Pharmacogenetics and Pharmacogenomics -- 16�Clinical Implementation of Translational Genomics -- 17�The Role of Genomics in Enabling Prospective Health -- 18�From Sequence to Genomic Medicine: Genome Policy Considerations -- 19�Federal Regulation of Genomic Medicine -- 20�Economic Issues and Genomic Medicine -- 21�Public Health Genomics -- �Section 4 - Clinical (Cardiology) -- 22�Hypertension -- 23�Lipiprotein Disorders -- 24�Myocardial Infarction -- 25�Acute Coronary Syndromes -- 26�Heart Failure in the Era of Genomic Medicine -- 27�Genomic Assessment of Cardiac Transplant Rejection -- 28�Hypertrophic Cardiomyopathy -- 29�Arrhythmias -- 30�Genetics and Genomics in the Management of Hemostasis & Thrombosis -- 31 Genomics of Congenital Heart Disease -- �Section 5 - Clinical (Oncology) -- 32�Genomics in the Management of Lymphomas -- 33�Genomics in Leukemias -- 34�Lung Cancer -- 35�Genomics in the Diagnosis and Management of Breast Cancer -- 36�Colorectal Cancer -- 37�Prostate Cancer -- 38�Genomic Assessment of Ovarian Cancer -- 39�Genomic Evaluation of Pancreatic Neoplasms -- 40�Genomic Evaluation of Head and Neck Cancer -- 41�Genomic Medicine, Evaluation of Brain Tumors and Gliomas -- 42�Diagnostic - Therapeutic Combinations in the Targeted Therapies for Treatment of Cancer -- �Section 6 - Clinical (Inflammatory Disease) -- 43�Genomics in the Evaluation and Management of Rheumatoid Arthritis -- 44?Omics" in the Genomic Evaluation of Multiple Sclerosis -- 45�Genomic Assessment of Inflammatory Bowel Disease -- 46�Asthma Genomics -- 47�Genomic Aspects in the Evaluation and Management of Chronic Obstructive Pulmonary Disease -- 48�Genetics and Genomics of Interstitial Lung Disease -- 49�Peptic Ulcer Disease -- �Section 7 - Clinical (Metabolic Disease) -- 50�Genomics in Pathogenesis of Cirrhosis -- 51�Genomic Medicine and Obesity -- 52�Diabetes -- �Section 8 - Clinical (Neurological Disease) -- 53�Genetics and Genomics of Dementia -- 54�Genetics and Genomics of Parkinson's Disease -- 55�Genomic Considerations in Opthamology -- 56�Genomics in the Diagnosis and Management of Depression -- �Section 9 - Clinical (Infectious Disease) -- 57?Genomic Approaches to -- the Host Response to Pathogens" -- 58�Host Genomics and Bacterial Infections -- 60�Diagnosis, Genomics, and the Management of Hepatitis --.#

Derived from the comprehensive two-volume set, Genomic and Personalized Medicine also edited by Drs. Willard and Ginsburg, this work serves the needs of the evolving population of scientists, researchers, practitioners and students that are embracing one of the most promising avenues for advances in diagnosis, prevention and treatment of human disease. From principles, methodology and translational approaches to genome discoveries and clinical applications, Essentials of�Genomic and Personalized Medicine will be a valuable resource for various professionals and students across medical disciplines, including human genetics and genomics, oncology, neuroscience, gene therapy, molecular medicine, pharmacology, and biomedical sciences. Updates with regard to diagnostic testing, pharmacogenetics, predicting disease susceptibility, and other important research components as well as chapters dedicated to cardiovascular disease, oncology, inflammatory disease, metabolic disease, neuropsychiatric disease, and infectious disease, present this book as an essential tool for a variety of professionals and students who are endeavouring into the developing the diverse and practical field of genomic and personalized medicine. * Full color throughout * Includes contributions on genetic counselling, ethical, legal/regulatory, and social issues related to the practice of genomic medicine from leaders in the field * Introductory chapter highlights differences between personalized and traditional medicine, promising areas of current research, and challenges to incorporate the latest research discoveries and practice * Ancillary material includes case studies and lab questions which highlight the collaborative approach to the science.

Electronic reproduction.
Amsterdam :
Elsevier Science & Technology,
2010.

Mode of access: World Wide Web.

ISBN: 9780123749345

Source: 176684:173111Elsevier Science & Technologyhttp://www.sciencedirect.comSubjects--Topical Terms:

72593

Index Terms--Genre/Form:

239592

LC Class. No.: RB155 / .E795 2010

Dewey Class. No.: 616.042

Essentials of genomic and personalized medicine
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505 0 $a 1�Introduction -- �Section 1 - Basics -- 2�Organization, Variation and Expression of the Human Genome -- 3�DNA Sequencing for the Detection?of Human Genome Variation -- 4�Genome-Wide Association Studies and Genotyping Technologies -- 5�Copy Number Variation and Human Health -- 6�DNA Methylation Analysis: Providing New Insight into Human Disease -- 7�DNA Microarrays in Biological Diversity and Patient Care -- 8�Proteomics: The Deciphering of the Functional Genome -- 9�Comprehensive Metabolic Analysis for Understanding Disease -- �Section 2 - Informatics -- 10�Bioinformatic and Computational Analysis for Genomic Medicine -- 11�Systems Biology and Systems Medicine -- 12�Electronic Medical Records in Genomic Medicine Practice and Research -- 13�Health Information Retrieval for Consumers -- �Section 3 - Translational -- 14�Genomics to Health:?Challenges and Opportunities -- 15�Pharmacogenetics and Pharmacogenomics -- 16�Clinical Implementation of Translational Genomics -- 17�The Role of Genomics in Enabling Prospective Health -- 18�From Sequence to Genomic Medicine: Genome Policy Considerations -- 19�Federal Regulation of Genomic Medicine -- 20�Economic Issues and Genomic Medicine -- 21�Public Health Genomics -- �Section 4 - Clinical (Cardiology) -- 22�Hypertension -- 23�Lipiprotein Disorders -- 24�Myocardial Infarction -- 25�Acute Coronary Syndromes -- 26�Heart Failure in the Era of Genomic Medicine -- 27�Genomic Assessment of Cardiac Transplant Rejection -- 28�Hypertrophic Cardiomyopathy -- 29�Arrhythmias -- 30�Genetics and Genomics in the Management of Hemostasis & Thrombosis -- 31 Genomics of Congenital Heart Disease -- �Section 5 - Clinical (Oncology) -- 32�Genomics in the Management of Lymphomas -- 33�Genomics in Leukemias -- 34�Lung Cancer -- 35�Genomics in the Diagnosis and Management of Breast Cancer -- 36�Colorectal Cancer -- 37�Prostate Cancer -- 38�Genomic Assessment of Ovarian Cancer -- 39�Genomic Evaluation of Pancreatic Neoplasms -- 40�Genomic Evaluation of Head and Neck Cancer -- 41�Genomic Medicine, Evaluation of Brain Tumors and Gliomas -- 42�Diagnostic - Therapeutic Combinations in the Targeted Therapies for Treatment of Cancer -- �Section 6 - Clinical (Inflammatory Disease) -- 43�Genomics in the Evaluation and Management of Rheumatoid Arthritis -- 44?Omics" in the Genomic Evaluation of Multiple Sclerosis -- 45�Genomic Assessment of Inflammatory Bowel Disease -- 46�Asthma Genomics -- 47�Genomic Aspects in the Evaluation and Management of Chronic Obstructive Pulmonary Disease -- 48�Genetics and Genomics of Interstitial Lung Disease -- 49�Peptic Ulcer Disease -- �Section 7 - Clinical (Metabolic Disease) -- 50�Genomics in Pathogenesis of Cirrhosis -- 51�Genomic Medicine and Obesity -- 52�Diabetes -- �Section 8 - Clinical (Neurological Disease) -- 53�Genetics and Genomics of Dementia -- 54�Genetics and Genomics of Parkinson's Disease -- 55�Genomic Considerations in Opthamology -- 56�Genomics in the Diagnosis and Management of Depression -- �Section 9 - Clinical (Infectious Disease) -- 57?Genomic Approaches to -- the Host Response to Pathogens" -- 58�Host Genomics and Bacterial Infections -- 60�Diagnosis, Genomics, and the Management of Hepatitis --.# $a
520 $a Derived from the comprehensive two-volume set, Genomic and Personalized Medicine also edited by Drs. Willard and Ginsburg, this work serves the needs of the evolving population of scientists, researchers, practitioners and students that are embracing one of the most promising avenues for advances in diagnosis, prevention and treatment of human disease. From principles, methodology and translational approaches to genome discoveries and clinical applications, Essentials of�Genomic and Personalized Medicine will be a valuable resource for various professionals and students across medical disciplines, including human genetics and genomics, oncology, neuroscience, gene therapy, molecular medicine, pharmacology, and biomedical sciences. Updates with regard to diagnostic testing, pharmacogenetics, predicting disease susceptibility, and other important research components as well as chapters dedicated to cardiovascular disease, oncology, inflammatory disease, metabolic disease, neuropsychiatric disease, and infectious disease, present this book as an essential tool for a variety of professionals and students who are endeavouring into the developing the diverse and practical field of genomic and personalized medicine. * Full color throughout * Includes contributions on genetic counselling, ethical, legal/regulatory, and social issues related to the practice of genomic medicine from leaders in the field * Introductory chapter highlights differences between personalized and traditional medicine, promising areas of current research, and challenges to incorporate the latest research discoveries and practice * Ancillary material includes case studies and lab questions which highlight the collaborative approach to the science.
533 $a Electronic reproduction. $b Amsterdam : $c Elsevier Science & Technology, $d 2010. $n Mode of access: World Wide Web. $n System requirements: Web browser. $n Title from title screen (viewed on Feb. 24, 2010). $n Access may be restricted to users at subscribing institutions.
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