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Real world drug discovery = a chemist's guide to biotech and pharmaceutical research /

紀錄類型:	書目-電子資源 : 單行本
正題名/作者:	Real world drug discovery/ Robert M. Rydzewski.
其他題名:	a chemist's guide to biotech and pharmaceutical research /
作者:	Rydzewski, Robert M.
出版者:	Amsterdam ;Elsevier, : 2008.,
面頁冊數:	xvii, 515 p. :ill. (some col.) ; : 26 cm.;
標題:	Drug development. -
電子資源:	An electronic book accessible through the World Wide Web; click for information
ISBN:	9780080466170

Real world drug discovery = a chemist's guide to biotech and pharmaceutical research /
Rydzewski, Robert M.

Real world drug discoverya chemist's guide to biotech and pharmaceutical research /[electronic resource] :Robert M. Rydzewski. - 1st ed. - Amsterdam ;Elsevier,2008. - xvii, 515 p. :ill. (some col.) ;26 cm.

Includes bibliographical references and index.

1 The Drug Discovery Business to Date -- 2 The Drug Discovery Business to Come -- 3 Industrial Considerations -- 4 How Things Get Done: The Project Team -- 5 Project Considerations -- 6 Hit Generation -- 7 Turning Hits into Drugs -- 8 Initial Properties -- 9 ADME and PK Properties -- 10 Toxicity-Related Properties -- 11 A Career in Drug Discovery.

Drug discovery increasingly requires a common understanding by researchers of the many and diverse factors that go into the making of new medicines. The scientist entering the field will immediately face important issues for which his education may not have prepared him: project teams, patent law, consultants, target product profiles, industry trends, Gantt charts, target validation, pharmacokinetics, proteomics, phenotype assays, biomarkers, and many other unfamiliar topics for which a basic understanding must somehow be obtained. Even the more experienced scientist can find it frustratingly difficult to get an overview of the many factors involved in modern drug discovery and often only after years of exploring does a whole and integrated picture emerge in the mind of the researcher. Real World Drug Discovery: A Chemist's Guide to Biotech and Pharmaceutical Research presents this kind of map of the landscape of drug discovery. In a single, readable volume it outlines processes and explains essential concepts and terms for the recent science graduate wondering what to expect in pharma or biotech, the medicinal chemist seeking a broader and more timely understanding of the industry, or the contractor or collaborator whose understanding of the commercial drug discovery process could increase the value of his contribution to it. Key Features: - Interviews with well-known experts in many of the fields involved, giving insightful comments from authorities on many of the sub-disciplines important to cutting edge drug discovery. - Helpful suggestions gleaned from years of experience in biotech and pharma, which represents a repository drug discovery "lore" not previously available in any book. - "Periodic Table of Drugs" listing current top-selling drugs arranged by target and laid out so that structural similarities and differences are plain and clear, with regular updates available at the book's website. - Extensive use of diagrams to illustrate concepts like biotech startup models, preteomic profiling for target identification, Gantt charts for project planning, etc.

Electronic reproduction.
Amsterdam :
Elsevier Science & Technology,
2009.

Mode of access: World Wide Web.

ISBN: 9780080466170

Source: 140428:140566Elsevier Science & Technologyhttp://www.sciencedirect.comSubjects--Topical Terms:

120365
Drug development.
Index Terms--Genre/Form:

96803
Electronic books.

LC Class. No.: RM301.25 / .R93 2008

Dewey Class. No.: 615.19

National Library of Medicine Call No.: QV 744 R992 2008

Real world drug discovery = a chemist's guide to biotech and pharmaceutical research /
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505 0 $a The drug discovery business to date -- The drug discovery business to come -- Industrial considerations -- how things get done : the project team -- Project considerations -- Hit generation -- Turning hits into drugs -- Initial properties -- ADME and PK properties -- Toxicity related properties -- A career in drug discovery research.
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