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Signal transduction

Record Type:	Electronic resources : Monograph/item
Title/Author:	Signal transduction/ Bastien D. Gomperts, Ijsbrand M. Kramer, Peter E.R. Tatham.
Author:	Gomperts, B. D.
other author:	Kramer, Ijsbrand M.
Published:	Amsterdam ;Elsevier/Academic Press, : c2009.,
Description:	xxvii, 810 p. :col. ill. ; : 26 cm.;
Subject:	Signal Transduction. -
Online resource:	An electronic book accessible through the World Wide Web; click for information
ISBN:	9780123694416

Signal transduction
Gomperts, B. D.

Signal transduction[electronic resource] /Bastien D. Gomperts, Ijsbrand M. Kramer, Peter E.R. Tatham. - 2nd ed. - Amsterdam ;Elsevier/Academic Press,c2009. - xxvii, 810 p. :col. ill. ;26 cm.

Includes bibliographical references and index.

Prologue: Signal Transduction, origins and ancestors -- First messengers -- Receptors -- GTP-binding proteins and signal transduction -- Effector enzymes coupled to GTP binding proteins: adenylyl cyclase and phospholipase C -- The regulation of visual transduction and olfaction -- Intracellular calcium -- Calcium effectors -- Phosphorylation and dephosphorylation: protein kinases A and C -- Nuclear receptors -- Growth Factors: Setting the framework -- Signalling pathways operated by receptor protein tyrosine kinases -- Signal transduction to and from adhesion molecules -- Adhesion molecules in the regulation of cell differentiation: Mainly about Wnt -- Activation of the innate immune system: the Toll-like receptor 4 and Signalling through Ubiquitylation -- Traffic of white blood cells -- Tyrosine protein kinases and adaptive immunity : TCR, BCR, soluble tyrosine kinases and NFAT -- Phosphoinositide 3-kinases, protein kinase B and signalling through the insulin receptor -- Protein Kinase C revisited -- Signalling through receptor serine/threonine kinases -- Protein dephosphorylation and protein phosphorylation -- Notch -- Targeting transduction pathways for research and medical intervention -- Protein domains and signal transduction.

Up-to-date, inclusive coverage of targeting transduction pathways for research and medical intervention * In-depth coverage of nuclear receptors, including steps in isolation of steriod hormones and the discovery of intracellular hormone receptors; Tyrosine protein kinases and adaptive immunity; and intracellular calcium * Extensive conceptual colour artwork to assist with comprehension of key topics * Instrumental margin notes highlight milestones in signalling mechanisms DESCRIPTION: Signal Transduction is a thorough, well-illustrated study in cellular signaling processes. Beginning with the basics, this book shows how cells respond to external cues, hormones, growth factors, cytokines, cell surfaces, etc., and further instructs how these inputs are integrated. Instruction continues with up-to-date, inclusive coverage of intracellular calcium, nuclear receptors, tyrosine protein kinases and adaptive immunity, and targeting transduction pathways for research and medical intervention. Signal Transduction serves as an invaluable resource for advanced undergraduates, graduate researchers, and established scientists working in cell biology, pharmacology, immunology, and related fields.

Electronic reproduction.
Amsterdam :
Elsevier Science & Technology,
2010.

Mode of access: World Wide Web.

ISBN: 9780123694416

Source: 113376:113466Elsevier Science & Technologyhttp://www.sciencedirect.comSubjects--Topical Terms:

256604
Signal Transduction.
Index Terms--Genre/Form:

96803
Electronic books.

LC Class. No.: QP517.C45 / G65 2009

Dewey Class. No.: 571.6

National Library of Medicine Call No.: 2009 J-375

Signal transduction
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100 1 $a Gomperts, B. D. $3 256601
245 1 0 $a Signal transduction $h [electronic resource] / $c Bastien D. Gomperts, Ijsbrand M. Kramer, Peter E.R. Tatham.
250 $a 2nd ed.
260 $a Amsterdam ; $a Boston : $c c2009. $b Elsevier/Academic Press,
300 $a xxvii, 810 p. : $b col. ill. ; $c 26 cm.
504 $a Includes bibliographical references and index.
505 0 $a Prologue: Signal Transduction, origins and ancestors -- First messengers -- Receptors -- GTP-binding proteins and signal transduction -- Effector enzymes coupled to GTP binding proteins: adenylyl cyclase and phospholipase C -- The regulation of visual transduction and olfaction -- Intracellular calcium -- Calcium effectors -- Phosphorylation and dephosphorylation: protein kinases A and C -- Nuclear receptors -- Growth Factors: Setting the framework -- Signalling pathways operated by receptor protein tyrosine kinases -- Signal transduction to and from adhesion molecules -- Adhesion molecules in the regulation of cell differentiation: Mainly about Wnt -- Activation of the innate immune system: the Toll-like receptor 4 and Signalling through Ubiquitylation -- Traffic of white blood cells -- Tyrosine protein kinases and adaptive immunity : TCR, BCR, soluble tyrosine kinases and NFAT -- Phosphoinositide 3-kinases, protein kinase B and signalling through the insulin receptor -- Protein Kinase C revisited -- Signalling through receptor serine/threonine kinases -- Protein dephosphorylation and protein phosphorylation -- Notch -- Targeting transduction pathways for research and medical intervention -- Protein domains and signal transduction.
520 $a Up-to-date, inclusive coverage of targeting transduction pathways for research and medical intervention * In-depth coverage of nuclear receptors, including steps in isolation of steriod hormones and the discovery of intracellular hormone receptors; Tyrosine protein kinases and adaptive immunity; and intracellular calcium * Extensive conceptual colour artwork to assist with comprehension of key topics * Instrumental margin notes highlight milestones in signalling mechanisms DESCRIPTION: Signal Transduction is a thorough, well-illustrated study in cellular signaling processes. Beginning with the basics, this book shows how cells respond to external cues, hormones, growth factors, cytokines, cell surfaces, etc., and further instructs how these inputs are integrated. Instruction continues with up-to-date, inclusive coverage of intracellular calcium, nuclear receptors, tyrosine protein kinases and adaptive immunity, and targeting transduction pathways for research and medical intervention. Signal Transduction serves as an invaluable resource for advanced undergraduates, graduate researchers, and established scientists working in cell biology, pharmacology, immunology, and related fields.
533 $a Electronic reproduction. $b Amsterdam : $c Elsevier Science & Technology, $d 2010. $n Mode of access: World Wide Web. $n System requirements: Web browser. $n Title from title screen (viewed on Feb. 24, 2010). $n Access may be restricted to users at subscribing institutions.
650 1 2 $a Signal Transduction. $3 256604
650 0 $a Cellular signal transduction. $3 126440
650 7 $a Transduction du signal cellulaire. $3 256605
655 7 $a Electronic books. $2 local. $3 96803
700 1 $a Kramer, Ijsbrand M. $3 319806
700 1 $a Tatham, Peter E. R. $3 256602
710 2 $a ScienceDirect (Online service) $3 254709
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856 4 0 $3 ScienceDirect $u http://www.sciencedirect.com/science/book/9780123694416 $z An electronic book accessible through the World Wide Web; click for information
994 $a C0 $b TEF