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Advances in medicinal chemistry.. Vo...
~
Reitz, A. B.
Advances in medicinal chemistry.. Volume 5
紀錄類型:
書目-電子資源 : 單行本
正題名/作者:
Advances in medicinal chemistry./
其他作者:
Reitz, A. B.
出版者:
[S.l.] :Elsevier Science, : 2000.,
面頁冊數:
1 v.
標題:
Pharmaceutical chemistry. -
電子資源:
http://www.sciencedirect.com/science/book/9780762305933
ISBN:
9780762305933
Advances in medicinal chemistry.. Volume 5
Advances in medicinal chemistry.
Volume 5[electronic resource]. - [S.l.] :Elsevier Science,2000. - 1 v.
Preface. Immunophilins: the next generation. Discovery of ABT-594 and related neuronal nicotinic acetylcholine receptor modulators as analgesic agents: medicinal chemistry and biology. Discovery and preclinical evaluation of novel dopamine partial agonists as antipsychotic agents. Nonpeptide inhibitors of HIV protease.
Volume 5 of Advances in Medicinal Chemistry contains four intriguing and detailed accounts of the close interface between synthetic chemistry, structure-activity relationships, biochemistry, and pharmacology. In Chapter 1, there is a comprehensive survey of the immunophilin area specifically focussing on neuroregenerative applications in the central nervous system. In Chapter 2, there is an overview of the development of a potent analgesic compound that works via modulation of neuronal nicotinic acetylcholine receptors. In Chapter 3, there is a description of dopamine D-2 autoreceptor partial agonists as potential therapy for the treatment of schizophrenia. In Chapter 4, there is a summary of the successful program in which potent non-peptide inhibitors of HIV protease from the AIDS virus were developed.
Electronic reproduction.
Amsterdam :
Elsevier Science & Technology,
2007.
Mode of access: World Wide Web.
ISBN: 9780762305933
Source: 126556:127737Elsevier Science & Technologyhttp://www.sciencedirect.comSubjects--Topical Terms:
199407
Pharmaceutical chemistry.
Index Terms--Genre/Form:
96803
Electronic books.
LC Class. No.: RS400 / .A35eb v. 5
Dewey Class. No.: 615/.19
Advances in medicinal chemistry.. Volume 5
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Volume 5 of Advances in Medicinal Chemistry contains four intriguing and detailed accounts of the close interface between synthetic chemistry, structure-activity relationships, biochemistry, and pharmacology. In Chapter 1, there is a comprehensive survey of the immunophilin area specifically focussing on neuroregenerative applications in the central nervous system. In Chapter 2, there is an overview of the development of a potent analgesic compound that works via modulation of neuronal nicotinic acetylcholine receptors. In Chapter 3, there is a description of dopamine D-2 autoreceptor partial agonists as potential therapy for the treatment of schizophrenia. In Chapter 4, there is a summary of the successful program in which potent non-peptide inhibitors of HIV protease from the AIDS virus were developed.
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